- Offers wide-ranging coverage of the current understanding of retinoblastoma
- Describes treatment approaches in detail
- Discusses molecular biology and genetics
- Includes a wealth of color and black and white images to aid understanding
This book is a comprehensive resource on the current understanding of retinoblastoma. It addresses all the essential aspects of retinoblastoma and its management, including: its molecular biology and genetics, management by focal treatment, intraarterial and intravitreal chemotherapy, electroretinogram monitoring of treatment, pharmacokinetic studies, high-risk features, treatment of metastatic disease, and long-term follow-up. The book represents a collaborative project involving ophthalmic oncologists, geneticists, pediatric oncologists, interventional neuroradiologists, electrophysiologists, and basic scientists who are at the forefront of their field. It is written in an accessible manner, and a wealth of tables, figures, and exemplary images are included to enhance the understanding of concepts. Contents- 1 Molecular Biology of Retinoblastoma - Scott D. Walter and J. William Harbour
- 2 Challenges of Genetic Susceptibility Testing for Retinoblastoma - Megan Harlan Fleischut
- 3 Technique of Intra-Arterial Chemotherapy for Retinoblastoma - Y. Pierre Gobin
- 4 Technique, Safety and Toxicity of Intravitreal Chemotherapy for Retinoblastoma - Jasmine H. Francis
- 5 Electroretinogram Monitoring of Retinoblastoma Treatment - Scott E. Brodie
- 6 Pharmacokinetics of Chemotherapy Delivered by Ophthalmic Artery Super-Selective Infusion - Paula Schaiquevich and Guillermo L. Chantada
- 7 Drug Discovery and Repurposing for Retinoblastoma - Bhavneet Bhinder, Jeni P. Mahida, Glorymar del Valle Ibáñez Sanchez, Kathryn Champ, Christophe Antczak, and Hakim Djaballah
- 8 Management of High Risk Retinoblastoma - Guillermo L. Chantada and María T.G. de Dávila
- 9 Treatment of Extraocular Retinoblastoma - Ira J. Dunkel and Ratna Behal
- 10 Second Tumors in Retinoblastoma Survivors - Ruth A. Kleinerman, Lindsay M. Morton, Jeannette R. Wong, and Margaret A. Tucker
- 11 Long-Term Follow-Up of Retinoblastoma Survivors - Danielle Novetsky Friedman
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