- The first authoritative book dedicated to the understanding of cholesterol and its effect on the body
- Provides a comprehensive overview of cholesterol crystal formation and methods for detection and treatment
- Discusses cholesterol and its effect across multiple diseases
This book is the first authoritative and comprehensive text dedicated to the understanding of how cholesterol triggers vascular inflammation and mechanical injury that leads to heart attacks, strokes as well as other organ and tissue pathology.
It includes chapters on the background of cholesterol crystal formation and methods for their detection as well as a description of the physiochemical transformation of metastable ‘liquid’ cholesterol to a solid flat plate crystalloid within the cellular and extracellular environment resulting in volume expansion. Chapters also discusses cholesterol crystals and other crystalloid molecules found in atherosclerotic plaque.
In addition, the book examines how cholesterol crystals can induce similar injurious processes in other organs including the retina of the eye to cause blindness, in solid cancers causing further tumor growth and in the brain of patients with Alzheimer’s.
And lastly, the book addresses various potential therapeutics that disrupt the physiochemical transformation of cholesterol from a liquid to a solid, inhibit its role in triggering inflammation and tissue injury while ushering a path towards targeted therapies.
Contents Overview- Overview
- Physical Properties and Imaging of Cholesterol Crystals: In Vitro
- Physical Properties and Imaging of Cholesterol Crystals: In Vivo
- Lipidology of Atherosclerosis
- Cholesterol Crystals and Tissue Injury
- Cholesterol Crystals and Inflammation
- Interaction of CCs with Other Crystalloids and Disease Conditions
- Treatment of Cholesterol Crystals
