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Succinct yet comprehensive, Aminoff's Diagnosis of Neuromuscular Disorders, 4th Edition, provides expert information and guidance on the clinical, electrodiagnostic, and imaging aspects of neuromuscular disorders. Fully updated, it reflects important advances in the field, including an improved understanding of the molecular and genetic basis of neuromuscular disease, an expanded use of next-generation genetic testing, refinements in electrodiagnosis, and the use of ultrasound imaging techniques to evaluate the peripheral nervous system. In-depth discussions of disease states, as well as the evidence supporting the use of electrodiagnostic and imaging techniques, moves this reference from simply answering the question “How?” to also answering “Why?” Features- Describes the range of clinical manifestations of individual neuromuscular diseases; the power and limitations of electrodiagnostic techniques as they relate to neuromuscular disorders; the place of genetic studies in the diagnosis and prognostication of these diseases; and the scope and utility of newer imaging procedures in detecting and localizing the underlying pathologic process.
- Reviews neuromuscular physiology and the pathology of major diseases.
- Provides a readable, well-illustrated synthesis of clinical and investigative techniques in diagnosing neuromuscular diseases, with concise guidance on how to conduct clinical, electrodiagnostic, and ultrasound evaluations and the findings in various disease states.
- Covers a wide variety of electrodiagnostic and ultrasound procedures, including techniques for evaluating different individual nerves-
- Features video clips of waveforms and of ultrasound images to illustrate key concepts.
- An ideal resource for neuromuscular specialists, clinical neurologists, physiatrists, rehabilitation specialists, clinical neurophysiologists, and electromyographers, as well as trainees and those preparing for board certification in neurology, PM&R, neuromuscular medicine, clinical neurophysiology, and electrodiagnostic medicine.
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Table of ContentsNew chapters are shown in bold type. The other chapters will be extensively revised and updated. INTRODUCTION - 1. Approach to Neuromuscular Diagnosis
(The aim of this new chapter is to share the thought process that experienced neuromuscular clinician use in making diagnoses.) - 2. Electrodiagnostic Methods for the Study of Nerve and Muscle
BASIC ASPECTS - 3. Nerve Physiology
- 4. Neuromuscular Junction Physiology
- 5. Muscle Physiology and the Motor Unit
- 6. Electrodiagnostic Apparatus
- 7. General Aspects of Needle Electromyography
- 8. Clinical Aspects of Needle Electromyography
- 9. Nerve Conduction Studies: Basic Principles and Pathologic Correlations
- 10. Quantitative and Related Techniques of Electromyography
- 11. Other Electrodiagnostic Techniques for the Evaluation of Neuromuscular Disorders
- 12. Electrophysiologic Evaluation of the Autonomic Nervous System
- 13. Magnetic Resonance Imaging of Nerve and Muscle in Health and Disease (A brief review of MR technology will be presented. The MR characteristics of healthy muscle and nerve will then be shared. Then, the imaging correlates to various diseases of muscle and nerve will be discussed.)
- 14. Neuromuscular Ultrasound (The technology and apparatus will first be introduced. The technique of conducting an evaluation will be presented. The imaging characteristics of normal muscle and nerve will be discussed before moving to a discussion of the correlates to common disease of muscle and nerve.)
CLINICAL ASPECTS - 15. Myopathic Disorders and Myalgia
- 16. Motor Neuron Disorders
- 17. Muscle Fiber and Motor Unit Hyperactivity States
- 18. Polyneuropathy and Mononeuropathy Multiplex
- 19. Root and Plexus Lesions
- 20. Neuromuscular Junction Disorders
NERVES IN THE UPPER EXTREMITIES - 21. Median Neuropathies
- 22. Ulnar Neuropathies
- 23. Radial Neuropathies
- 24. Disturbances of Other Nerves in the Upper Extremities
NERVES IN THE LOWER EXTREMITIES - 25. Peroneal Neuropathies
- 26. Tibial and Sural Neuropathies
- 27. Sciatic Neuropathies
- 28. Disturbances of Other Nerves in the Lower Extremities
- 29. Facial Neuropathies
- 30. Disturbances of Other Cranial Nerves and the Phrenic Nerve
CENTRAL NERVOUS SYSTEM - 31. Electrophysiologic Evaluation of Selected Aspects of the Central Nervous System
- Appendix:
A Glossary of Terms Used in Clinical Electromyography
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