- Offers a detailed guide to MR-Linac, a unique and fast growing radiation treatment modality
- Covers the physics, technology, and clinical applications of MR-Linac
- Includes future considerations for this new technology
This book offers a detailed guide to MR-Linac, a unique and fast growing radiation treatment modality.
MR-linac is new technology that is a fusion of an MRI and a linear accelerator on the same gantry. It can change both target volume delineation and tumor visualization in real time using MR-cine images and treatment. Tumor location changes moment to moment as radiation is delivered, but this cannot be visualized in current radiation therapy practices. This new and rapidly growing technology can provide adaptive therapy that was not possible before.
This book presents current knowledge on MR-linac technology, clinical practices, and ultimately patient outcome where dose escalation is not possible due to limiting normal tissue structures in the vicinity of tumor. There are two commercial MR-linac machines under consideration and both will be covered in detail. The book is divided into four sections.
The first gives a general introduction to MR-Linac, covering the role of MRI in radiation oncology, the clinical necessity of this technology, and patient selection. The next section details the physics and technology of MR-Linac, covering image sequence, motion management, and treatment planning. Section three offers the clinical applications of MR-Linac and is divided by body area, including lung, prostate, and breast. Finally, the fourth section looks to the future and what this technology can mean for radiation oncology.
This is an ideal guide for radiation oncologists, medical physicists, and relevant trainees.
Table of Contents- Introduction to MR-Linac
- Role of MRI in Radiation Oncology
- Clinical Necessity and Patient Selection in MR-Linac
- Education and Training in MR-Based Radiation Treatment
- An Introduction to MR Sequences Used in Oncology with Application to MR-Linac
- Motion Management and Tracking
- sCT and Dose Calculation
- Treatment Planning Considerations for an MR-Linac
- The First Low-Field MRI-Guided Radiation Therapy Hybrid Integrated System: MRIdian
- Elekta Unity System
- The Alberta Rotating Biplanar Linac-MR, a.k.a., Aurora-RT™
- Clinical Applications of MR-Linac in Oligometastatic Disease
- Management of Pancreatic Cancer with MRI-Guided Adaptive Radiotherapy
- The Role of MR-Guided Radiation Therapy in the Management of Liver Malignancies
- Magnetic Resonance Imaging-Guided Radiation Therapy: Advances and Opportunities for Thoracic Malignancies
- MRI-Guided Radiation Therapy for Prostate Cancer: Less Is More When Technology and Evidence Intersect
- Breast Radiotherapy Using MR-Linac
- Considerations for Using MR Linac for the Treatment of Patients with Gynecologic Cancer: A Practical Guide and Early Clinical Experience
- MR-Guided Radiotherapy in the Pediatric and Adolescent Patient
- MR-Linac-Guided Adaptive Radiotherapy for Brain Tumors
- Treatment of Head and Neck Cancers with MR-Linac
- The Australian MRI-Linac: A 10-Year Journey
- Low-Field MR Imaging
- Image-Based Biomarkers in Magnetic Resonance-Guided Radiotherapy (MRgRT)
- Epilogue and Outlook
