Dupuytren's Disease: A Scientific Review offers consolidated, up-to-date coverage of both the basic normal (nonpathologic) science and cutting-edge science of this progressive disorder. Drs. Lawrence C. Hurst, Marie A. Badalamente, and David Edward Komatsu break down the complex topic of Dupuytren's contracture into its basic scientific components. Hand surgeons, plastic surgeons, and orthopaedic surgeons will find this unique, concise title to be especially helpful in their practices.
- Includes chapters on prevalence of Dupuytren's disease, normal genetics and the genetic abnormalities associated with Dupuytren's disease, and collagen and collagen synthesis in healthy fascia and Dupuytren's disease.
- Provides numerous illustrations throughout.
- Contains an in-depth bibliography and a useful, complete glossary of related terms.
- Consolidates today's available information on Dupuytren's science into a single, convenient resource.
Table of Contents1. Prevalence of Dupuytren's disease
2. Epidemiology of Dupuytren's disease
3. Anatomy and pathoanatomy of Dupuytren's disease
4. Normal genetics and the genetic abnormalities associated with Dupuytren's disease
5. Cells of normal fascia and cells of Dupuytren's disease
6. Growth factors; cytokines; free radicals in healthy fascia and Dupuytren's disease
7. Normal microRNA and abnormal microRNA findings seen with Dupuytren's disease
8. Collagen and collagen synthesis in healthy fascia and Dupuytren's disease
9. Collagenases and collagenase use in Dupuytren’s Disease
10. Extra cellular matrix in healthy fascia and Dupuytren's disease
11. Potential therapies suggested by Dupuytren’s science
12. Conclusion -Key Points Summary
