- Covers state-of-the-art topics covering this emerging area
- Provide the perspectives on the subject from basic, translational and clinical research
- Useful reference for graduate students, basic researchers as well as physicians
This book covers state-of-the-art topics covering evidences indicate that the gut microbiota can be harnessed for cancer prevention as well as to modulate the efficacy of chemotherapy and immunotherapy.
This book includes: 1) characterization of the dysregulated microbiome in gastrointestinal cancers (Chapters 1-6); 2) the molecular mechanism of action of gut microbiota via microbial metabolites and direct interaction with host cancer or immune cells (Chapters 7-11); 3) key methodologies for studying the role of gut microbiota in cancers (Chapters 12-13); and 4) the potential application of gut microbes for the prevention and treatment of gastrointestinal cancers (Chapters 14-17).
The contributors are international experts in molecular and cellular biology, microbiology, metabolomics, bioinformatics and physician scientists to provide in-depth reviews of this subject
This book provides a rich resource of information on this important topic for graduate students, basic researchers and physicians.
Table of Contents- Introduction.-
- Gut microbiome in health and diseases.-
- Microbiome in colorectal cancer.-
- Microbiome in gastric cancer.-
- Microbiome in liver cancer.-
- Virus, fungi and archaea in gastrointestinal cancer.-
- Microbial metabolomics in gastrointestinal cancer.-
- Diet and gut microbiome in gastrointestinal cancer.-
- Diet and gut microbiome in fatty liver and its associated liver cancer.-
- Host-microbiome interaction in gastrointestinal cancer.-
- Gut microbiome and immune responses in gastrointestinal cancer.-
- Animal models in the study of microbiome in gastrointestinal cancer.-
- High-throughput sequencing data analyses for microbiome profiling.-
- Gut microbiota modulation: probiotics and prebiotics in gastrointestinal cancer.-
- Roles of gut microbiota in efficacy of anticancer treatment of gastrointestinal cancer.-
- Targeting gut microbiota to treat gastrointestinal cancer.
