Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson’s and related disorders.
With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders.
Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s disease and related disorders.
Features:- Comprehensive overview of biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders
- Helps readers understand the in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders
- Discusses the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s and related disorders
Table of ContentsSection I. Introduction
1. Parkinson’s disease and related disorders: The pursuit for reliable readouts and the role of neuroimaging
2. Advances in Magnetic Resonance Imaging
3. Advances in Molecular Imaging Methodology
Section II. Clinical Applications in Parkinson Disease
4. Dopaminergic molecular imaging in familial and idiopathic PD
5. Serotonergic molecular imaging in familial and idiopathic PD
6. Other systems PET and SPECT imaging in familial and idiopathic PD
7. Structural MRI in familial and idiopathic PD
8. Functional MRI in familial and idiopathic PD
9. Molecular imaging in Prodromal PD
Section III. Clinical Applications in Lewy Body Dementias
10. Molecular Imaging evidence in favor or against PDD & DLB overlap
11. MR Imaging in PD-MCI, PDD & DLB
Section IV. Clinical Applications in Atypical Parkinsonian Disorders
12. Neuroimaging in MSA
13. Neuroimaging in PSP
14. Neuroimaging in CBS
Section V. Clinical Applications in Other Movement Disorders
15. Molecular imaging in Huntington's Disease
16. Magnetic Resonance Imaging in Huntington’s disease
17. Neuroimaging in Essential Tremor
18. Neuroimaging in Restless leg syndrome
19. Neuroimaging in Dystonia
20. Demyelination Syndromes and Movement Disorders
Section VI. Conclusions
21. The Future of Neuroimaging and the Application for Robust Measures in Clinical Trials
