Spinal Interneurons: Plasticity after Spinal Cord Injury provides neuroscientists, clinicians and trainees a reference book exclusively concentrating on spinal interneurons and the techniques and experiments employed to identify and study these cells as part of normal, diseased and injured neural circuits.
In addition, the book highlights the therapeutic potential of these cells by presenting relevant pre-clinical and clinical work that has been performed. The book's focus on the latest in therapeutic strategies for targeting spinal interneurons, considerations for the development and use of treatments, and how such treatments work make this a comprehensive source of information.
Features- Provides a comprehensive overview of the techniques used to identify, characterize and classify spinal interneurons and their role in neural circuits
- Presents an in-depth discussion of the therapeutic potential of spinal interneurons for SCI injury and/or diseases
- Represents the first book to discuss spinal interneurons and translational research
Table of ContentsSection 1: Spinal Interneurons: Motor and Sensory Neuronal Networks- 1. Spinal Interneurons: coordination and modulation in the adult spinal cord
- 2. Identifying spinal interneurons: lessons from developmental biology and genetics
- 3. Spinal Interneurons and Motor Function
- 4. Spinal interneurons and Sensory Function
- 5. Lessons from computational models
Section 2: Spinal Interneurons: A role in injury and disease- 6. Spinal interneurons after spinal cord injury: Adaptive vs maladaptive neuroplasticity
- 7. Spinal interneurons and Breathing
- 8. Spinal interneurons and Bladder function
- 9. Spinal interneurons and Pain
- 10. Spinal interneurons in pre-clinical models of ALS
Section 3: Spinal Interneurons: A therapeutic target for plasticity, repair and recover- 11. Introduction: Therapeutic potential of spinal interneurons Electrical stimulation
