- Written by leading international
- Explores the close connection between immunology and nuclear medicine
- Discusses the growing role of nuclear medicine and molecular imaging in the diagnosis and treatment of cancer
This book explores the close connection between immunology and nuclear medicine, which has led to radioimmunoimaging and radioimmunotherapy (RIT).
Molecular imaging with positron emission tomography (PET) and single-photon emission computed tomography (SPECT) is increasingly being used to diagnose, characterize, and monitor disease activity in the context of inflammatory disorders of known and unknown etiology, such as sarcoidosis, atherosclerosis, vasculitis, inflammatory bowel disease, rheumatoid arthritis, and degenerative joint disease.
The first chapters discuss the various radiopharmaceutical agents and radiolabeled preparations that have been employed in inflammation imaging. Of these, FDG-PET imaging has been shown to have the great value in the detection of inflammation and has become the centerpiece of several initiatives over the last several years. This very powerful technique will play an increasingly important role in the management of patients with inflammatory conditions in the future.
The book also explores the growing role of nuclear medicine and molecular imaging in the diagnosis and treatment of cancer. The rapid pace of change has been fueled by advances in our understanding of tumor biology, on the one hand, and the development of specifically targeted medical therapies, diagnostic agents, and radiotherapies, on the other.
Written by leading international experts in the field, this book is an invaluable tool for nuclear medicine physicians, radiologists, oncologists, and immunologists.
Table of Contents- Introduction on Nuclear Medicine and Immunology
- Nuclear Imaging of Endogenous Markers of Lymphocyte Response
- Radioimaging of Activated T Cells in Preclinical and Clinical Cancer Investigations
- Gallium Imaging of Infection and Inflammation
- 111Indium-Labeled Leukocyte Imaging of Infection and Inflammation
- [99mTc]Tc-HMPAO-Labeled Leukocyte Imaging of Infection and Inflammation
- 2-[18F]FDG PET Imaging of Infection and Inflammation
- 2-[18F]FDG PET/CT in Fever of Unknown Origin
- Tumor-Targeting Agents
- Tumor Architecture and Targeted Delivery
- Radionuclide Therapy and Immunomodulation
- Translational Development and Testing of Theranostics in Combination with Immunotherapies
- Radioimmunotherapy
- Radiolabeled Antibodies for Cancer Radioimmunotherapy
- Dosimetric Principles of Targeted Radiotherapy and Radioimmunotherapy
- Theranostics of Hematologic Disorders
- Radioimmunotherapy of Acute Leukemia
- Targeted Radionuclide Therapy and Immunotherapy of Metastatic Prostate Cancer
- Radioimmunotherapy and Targeted Radiotherapy of Squamous Cell Carcinoma of the Head and Neck
- The Use of PET in Evaluating the Efficacy of Immunotherapy in Oncology
- Moving Forward: Expected Opportunities for the Development of New Therapeutic Agents
