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- Comprehensive overview of theory and research by distinguished clinicians, research scientists, and biotechnologists
- Extensive discussion of cancer molecular biology
- Coverage of many topics of high current interest
Head and neck cancer (HNC) is a heterogeneous group of cancers that, if combined, represent one of the most common cancer types. Patients with HNC suffer significant morbidity and mortality due to the importance of the structures involved. Over two-thirds of these patients are diagnosed at a late stage, leading to a poor prognosis. Therefore, advancements in early detection and treatment of HNC are crucial. This second volume provides an up-to-date overview of the theoretical background in the field of head and neck cancer (HNC) as well as of the emerging research that is impacting our understanding of this disease. The book begins with a comprehensive review of the epidemiology, etiology, symptoms, diagnosis, and staging of HNC. Next, it covers the essentials of potentially malignant disorders of the oral cavity, an important variety of HNC. Subsequently, it covers the newly emerging research in the field of HNC. The overall goal is to shift towards precision medicine (discussed in detail in Volume I), which will bring individualized clinical benefit to patients with HNC. This second volume of Early Detection and Treatment of Head & Neck Cancers concludes with the topic of chronic pain associated with HNC, including both the mechanisms of pain and the management strategies, and the emerging oral mucoadhesive drug delivery approach for HNC. All HNC surgeons, scientists, residents, and individuals whose lives have been touched by this disease, will recognize the impact pain has upon a patient’s health and his or her recovery trajectory. Table of Contents- General Introduction to Head and Neck Cancer: Etiology, Symptoms, Diagnosis, Staging, Prevention, and Treatment
- Potentially Malignant Disorders of the Oral Cavity
- Diagnosis and Management of Intraoral Epithelial Dysplasia
- Dysphagia in Head and Neck Cancers
- The Mutational Landscape of Head and Neck Squamous Cell Carcinoma: Opportunities for Detection and Monitoring Via Analysis of Circulating Tumor DNA
- Circulating Biomarkers in Head and Neck Cancer
- Proinflammatory Signaling Pathways and Genomic Signatures in Head and Neck Cancers
- Pain Associated with Head and Neck Cancers
- Emerging Trends in Oral Mucoadhesive Drug Delivery for Head and Neck Cancer
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