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- Presents a comprehensive, up-to-date description of the anatomy, function, dysfunction, and diseases of the hypothalamus, including clinical management
- Discusses hormone excess and deficiency, obesity and wasting, sleep disorders, tumors and mass lesions, ROHHAD, and idiopathic and iatrogenic diseases of the hypothalamus, among other topics
- An excellent resource for endocrinologists, neurologists, neurosurgeons, psychiatrists, residents and fellows in these areas
The hypothalamus is an anatomically small but functionally important part of the brain. In functional and pathophysiological terms, the hypothalamus represents the intersection of several areas of clinical and medical expertise. The human hypothalamus can be astutely referred to as the crossroad of endocrinology, psychiatry, neurology and neurosurgery. Because of its involvement in myriad physiologic functions and the varied ways disorders involving it can manifest, hypothalamic disease can initially come to medical attention in widely disparate settings and with widely different clinicians. Therefore, the detection and proper care of hypothalamic dysfunction and disease often requires carefully coordinated multidisciplinary care. This volume fills a significant void in the medical professional community, comprehensively presenting the scope of hypothalamic structure, function, dysfunction and disease to cater to the various clinical, teaching and research professionals that have a stake in this part of the human brain. This text captures in one place all the information that practicing clinicians, clinician scientists, and researchers need to be adequately informed about various aspects of the hypothalamus in all its complexity. It is comprehensive and broad in scope so that it provides relevant reference information for the wide range of professionals involved in the pre- and post-mortem detection, diagnosis, characterization, care and management of various hypothalamic disorders and diseases in addition to providing a sound anatomic and physiologic foundation of the normal human hypothalamus. The Human Hypothalamus can be used to differing degrees by medical professionals and students alike, finding utility for interested general clinicians, medical school and allied health professional teaching faculty as well as subspecialists in domains as wide as neurosurgery, neuroendocrinology, clinical psychiatry and neuro-oncology. Table of Contents- Introduction to the Hypothalamus: Correlates From Animal Studies
- Anatomy and Topography of the Hypothalamus
- Neuroimaging of the Human Hypothalamus
- Neurophysiology of the Hypothalamus
- Neuroendocrinology of the Hypothalamus and Pituitary Axes
- Imaging Aspects of Pathologies of the Sella, the Pituitary Gland, and the Hypothalamus
- Neurological Syndromes of the Hypothalamus
- Neuropsychiatric and Neurobehavioral Syndromes of the Human Hypothalamus
- Neurosurgical Aspects of Hypothalamic Disease
- Hormone Excess Syndromes of the Hypothalamic-Pituitary Axis
- Hormone Deficiency Syndromes of the Hypothalamic-Pituitary Axis
- Hypothalamic Obesity and Wasting Syndromes
- Hypothalamic Sleep Disorders
- Genetic Syndromes of Hypothalamic Dysfunction
- Neuroendocrine Neoplasms and Lesions of the Hypothalamus
- Non-endocrine Neoplasms of the Hypothalamus
- Nonneoplastic Mass Lesions of the Hypothalamus
- Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation/Neuroendocrine Tumor (ROHHAD/NET) syndrome
- Infectious Diseases of the Hypothalamic-Pituitary Axis
- Inflammatory Conditions of the Hypothalamus
- Traumatic and Degenerative Hypothalamic Diseases
- Iatrogenic Hypothalamic Disorders
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