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Cardiovascular Calcification and Bone Mineralization


Cardiovascular Calcification and Bone Mineralization

563 Seiten, 1. Auflage, 2020
108 Abbildungen

  • Discusses treatments in bone disorders and ongoing therapeutic efforts in cardiovascular calcification
  • Provides clinical strategies that may be applicable to many types of cardiovascular diseases
  • Examines the physiological and pathological processes of cardiovascular and ectopic calcification as well as bone mineralization
  • Aggregates knowledge from across disparate calcification disciplines
The book covers the basic science and clinical aspects of cardiovascular calcification and bone mineralization. Cardiovascular calcification is the leading predictor of cardiovascular morbidity and mortality, with a predictive value more significant than blood lipid levels. The presence of calcific mineral in cardiovascular tissues alters biomechanical performance, increasing workload on the heart and potentiating atherosclerotic plaque rupture and subsequent heart attack and stroke.

This book examines the role of calcification in cardiovascular disease covering topics such as calcification in the atherosclerotic plaques and aortic valves arteries and valves, aortic valve replacement, peripheral artery disease, imaging of early calcification and target discovery. In addition, various forms of ectopic calcification as well as mechanisms of bone mineralization are discussed.

Cardiovascular Calcification and Bone Mineralization is an essential resource for clinicians, researchers, and other medical professionals in cardiology, pathology, and biomedical engineering.

Table of Contents

Part I. Cardiovascular Calcification
  • Pathology of Arterial and Valvular Calcification
  • Developmental Pathways in Cardiovascular Calcification
  • Differential Mechanisms of Arterial and Valvular Calcification
  • Calcification in Aortic Valve Replacement
  • Role of Extracellular Vesicles in Cardiovascular Calcification
  • Biomechanics, Mechanobiology, and Cardiovascular Calcification
  • Cardiovascular Calcification in Diabetics
  • Cardiovascular Calcification in Chronic Kidney Disease
  • Cardiovascular Calcification in Peripheral Artery Disease
  • Cardiovascular Calcification in Pediatrics and Progeria
  • Imaging of Early Calcification
  • Calcification Paradox - Bone vs Vascular Calcification
  • Clinical Trials in Cardiovascular Calcification
Part II. Ectopic Calcification
  • Calcification in the Brain
  • Calcification in the Kidney
  • Calcification in the Liver and Lungs
  • Placental Calcification in Newborns and its Clinical Implications
  • Breast Cancer Microcalcification
  • Calcification Following Traumatic Blast Injury
Part III. Bone Mineralization
  • Extracellular Matrix and Mineralization in Skeletal Development
  • Cellular Contributors to Bone Homeostasis
  • Biomechanics and Mechanobiology in Bone Remodeling
  • Osteogenesis Imperfecta and Congenital Disorders
  • Therapeutic Strategies for Pathological Bone Remodeling

Günstige Softcover Ausgabe der 1. Auflage 2020 Hardcover statt 213,99 €

€ 149,79
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