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- This collection of reports on OPLL is amply augmented with illustrations
- Brings together information on all aspects of OPLL - epidemiology, etiology, diagnosis, and treatment
- Until now little has been published on the subject in English
This book brings together information on all aspects of ossification of the posterior longitudinal ligament (OPLL), a hyperostotic condition of the spine that can cause severe neurological deficits. Since the second edition of this book was published in 2006, there have been tremendous advances in the field, and this third edition provides updated information on the disease’s epidemiology, diagnosis and treatment, while also addressing ossification of the ligamentum flavum (OLF) and diffuse idiopathic spinal hyperostosis. As such, it offers a valuable resource for all those who want to gain a deeper understanding of OPLL/OLF and those involved in making decisions about its treatment. Table of ContentsPart 1 IntroductionPart 2 Epidemiology - 2 An Overview of Epidemiology and Genetics
- 3 OPLL: Disease entity, prevalence, literature research, and growth
- 4 Natural History of Ossification of the Posterior Longitudinal Ligament (OPLL)
Part 3 Pathology & Pathogenesis - 5 Overview of Recent Basic Researches on OPLL and OLF
- 6 Histopathological Features of Ossification of the Posterior Longitudinal Ligament
- 7 Ectopic Ossification of Human Spinal Ligaments Caused by Mesenchymal Stem Cell Abnormalities
- 8 A Short History of Genetic Study of OPLL
- 9 Overview of possible roles of OPLL-associated genes in OPLL development
- 10 Application of iPS cell technology for OPLL
- 11 Mechanisms underlying OPLL development in Tiptoe Walking (ttw) Mice
- 12 In vivo tracing of neural tracts in tip-toe walking Yoshimura mice by diffusion tensor tractography
- 13 Metabolomics analysis in OPLL patients
Part 4 Diagnosis - 14 Diagnosis of OPLL and OLF: overview
- 15 Clinical manifestation of cervical OPLL
- 16 Three-dimensional imaging of cervical ossification of the posterior longitudinal ligament
- 17 Clinical manifestations of thoracic ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligament flavum (OLF)
- 18 Evaluation of distribution patterns of spinal ligament ossification using whole-spine computed tomography in patients with cervical ossification of the posterior longitudinal ligament
- 19 Diagnostic imaging of thoracic OPLL and OLF
- 20 Biomechanics of the spinal cord compression due to cervical ossification of the posterior longitudinal ligament
Part 5 Treatment 21 Surgical Indications and Choice of Surgical Procedure for Cervical Ossification of the Longitudinal Ligament- 22 Overview of Laminoplasty
- 23 Open-door Laminoplasty for Cervical OPLL: Technique, Long-term Results, and Complications
- 24 Double-door Laminoplasty for Cervical OPLL : Technique, Complications and Long-term Results
- 25 Posterior Decompression and Fusion for Cervical OPLL: Indication and Technique
- 26 Anterior Cervical Decompression for Cervical OPLL: Technique, Complications and Long-term Results
- 27 Surgical Indications and Choice of Surgical Procedure for Thoracic OPLL
- 28 Posterior decompression and fusion for thoracic OPLL: surgical techniques, outcomes, timing and complications
- 29 Anterior Decompression and Fusion for Thoracic OPLL: Transthoracic and Transsternal Approaches
- 30 Circumferential Decompression Through Posterior Approach for Thoracic OPLL: Technique and Complications
- 31 Surgery for ossification of the ligamentum flavum: posterior decompression with or without fusion
- 32 Computer-Aided Surgery for Ossification of the Spinal Ligaments
- 33 Surgical Treatment of Thoracic Ossification of the Posterior Longitudinal Ligament: Intraoperative Spinal Cord Monitoring
- 34 Intraoperative ultrasonography for patients with ossification of the posterior longitudinal ligament
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