- Offers a valuable translational work on cardiovascular biology, bridging the gap between clinics and basic science
- Written by top lecturers and outstanding students from the Imperial College London
- Places particular emphasis on novel and controversial topics
This textbook introduces readers to the scientific basics of cardiovascular medicine and biology. It covers not only developmental but also cellular and molecular aspects of normally functioning vasculature and the heart; importantly, it also addresses the mechanisms leading to and involved in specific cardiovascular diseases. Though the main emphasis is on novel therapies and potential therapeutic targets, specific controversial topics like cardiac remodeling and regenerative capacities are also addressed.
All chapters were written by lecturers from the Imperial College London, in collaboration with their students from the College’s BSc Programme in Medical Sciences with Cardiovascular Science. Bridging the gap between clinics and basic biology, the book offers a valuable guide for medical students, and for Master and PhD students in Cardiovascular Biomedicine.
Table of ContentsCardiac Development and Congenital Heart Disease- Cardiac Development Biology - Early Mechanisms
- Cardiac Development Biology - Late Mechanisms
- Cardiomyocyte Structure and Function
- Cardiac Morphology - Anatomy of Congenital Heart Disease
- Common Congenital Abnormalities
The Science of Arrhythmia- Introduction to the Action Potential
- Ion transporters and their Properties
- Excitation Contraction Coupling
- Tachyarrhythmias
- Bradyarrhythmias
The Science of Heart Failure- Cardiac Contractility - Normal and Pathological
- Heart Failure - A Scientific Perspective
- Cardiomyopathy
- Therapeutics
- Novel Therapies
The Science of Vascular Disease- The Vasculature - Pharmacological Targets
- The Coagulation Cascade and its Therapeutic Modulation
- Cellular and Molecular Mechanisms of Atherosclerosis
- Cellular and Molecular Mechanisms of Angiogenesis
- Endothelial Function and Dysfunction
