- Offers comprehensive information on the role of free radicals in heart diseases
- Serves as a valuable resource for identifying drug targets for cardiovascular diseases
- Provides interesting facts, real laboratory data and tips for designing experiments in the specified areas
This book bridges the gap between fundamental and translational research in the area of heart disease.
It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS generating enzymes; and oxidant induced signaling pathways and their antagonists that allow subtle modulation of redox signaling, it also discusses the spatial and temporal aspects of oxidative stress in the cardiovascular system, which are of vital importance in developing better strategies for treating heart disease. Each chapter offers researchers valuable insights into identifying targets for drug development for different types of heart disease.
Table of Contents- Oxidative Stress and Cardiovascular Risk and Prevention in Children and Adolescents
- The Role of Redox Signalling in Cardiovascular Regeneration
- Oxidative Stress-Driven Cardiotoicity of Cancer Drugs
- Molecular Targets and Novel Therapeutics to Target Oxidative Stress in Cardiovascular Diseases
- Dietary Antioxidants in Mitigating Oxidative Stress in Cardiovascular Diseases
- Reactive Oxygen Species and Their Epigenetic Consequences in Heart Diseases
- Metabolic Signatures of Redox-Dependent Cardiovascular Diseases
- Cardio Protective Influence of Dietary Spices Mediated Through Their Hypolipidemic and Antioxidant Potential
- Oxidative Stress and Modulation of Cardiac Kv1.5 Channel
- Aging and Cardiovascular Diseases: The Role of Cellular Senescence
- Influence of Genetic Factor on Oxidative Stress Mediated Heart Damage
- Oxidative Stress in Cardiac Remodeling Post-Ischemia/Reperfusion: Friend or Foe?
- Redox Aspects of Myocardial Ischemia/Reperfusion Injury and Cardioprotection
- Role of Oxidative Stress in Myocardial Ischemia and Infarction
- Oxidant Stress in Atherosclerosis: Oxidatively Modified LDL and LOX-1
- Role of Oxidative Stress and Cardiovascular Risk Factors in Ischemic Heart Disease
- Oxidative Stress and Labile Zinc in Heart Dysfunction Under Hyperglycemia
- Histone Deacetylases and Oxidative Stress: Role in Diabetic Cardiomyopathy
- Regulating Inflammatory Cytokines in the Diabetic Heart
- Advanced Glycation End Products: A Potential Contributor of Oxidative Stress for Cardio-Vascular Problems in Diabetes
- Role of iNOS in Insulin Resistance and Endothelial Dysfunction
- Oxidative Stress Mechanisms in Type 2 Diabetes Induced Coronary Heart Disease
- Role of Oxidative Stress in the Pathophysiology of Arterial Hypertension and Heart Failure
- Pulmonary Hypertension and the Right Ventricle: The Roles of Mitochondrial Reactive Oxygen Species in Causing Further Right Ventricular Mitochondrial Changes
- Mitochondrial Dysfunction and Oxidative Stress: Focusing on Cardiac Hypertrophy and Heart Failure
- Oxidative Stress in Hypertension and Cardiovascular-Renal Remodeling: Focus on the Renin-Angiotensin-Aldosterone System
