- Broadens the understanding of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO)
- Offers practical guidance on usage from imaging to data analysis
- Comprehensive reference of state-of-the-art literature on Fluorescene Lifetime Imaging in Retinal Diagnsostics
This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO).
FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies.
This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis.
Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
Table of Contents- Introduction
- FLIO Technique and Principles
- FLIO Historical Background
- Fluorescence Lifetime Imaging Microscopy
- The Fluorescence Lifetime Imaging Ophthalmoscope
- Image Acquisition and Analysis
- Fluorophores in the Eye
- FLIO in the Healthy Eye
- FLIO in Retinal Diseases
- Age-Related Macular Degeneration
- FLIO in Diabetic Retinopathy
- Retinal Artery Occlusion
- Central Serous Chorioretinopathy
- Macular Telangiectasia Type 2
- Hereditary Retinal Diseases: Stargardt, Choroideremia, Retinitis Pigmentosa
- Macular Pigment
- Fluorescence Lifetime Imaging Ophthalmoscopy in Alzheimer’s Disease
- FLIO in Mouse Models
- Discussion and Summary
