Up-to-date, authoritative and comprehensive,
Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald's Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies.
Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients.
- Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems
- Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines
- Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs)
- Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure
- Covers the pathophysiological basis for the development and progression of heart failure
- Serves as a definitive resource to prepare for the ABIM's Heart Failure board exam
- 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition)
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices
Table of ContentsSection 1 Basic Mechanisms of Heart Failure
- 1. Molecular Basis for Heart Failure
- 2. Cellular Basis for Heart Failure
- 3. Cellular Basis for Myocardial Regeneration and Repair
- 4. Myocardial Basis for Heart Failure: Role of Cardiac Interstitium
Section 2 Mechanisms of Disease Progression in Heart Failure
- 5. Molecular Signaling Mechanisms of the Renin-Angiotensin System in Heart Failure
- 6. Adrenergic Receptor Signaling in Heart Failure
- 7. Role of Innate Immunity in Heart Failure
- 8. Oxidative Stress in Heart Failure
- 9. Natriuretic Peptides in HF
- 10. Systolic Dysfunction in Heart Failure
- 11. Alterations in Ventricular Function: Diastolic Heart Failure
- 12. Alterations in Ventricular Structure: Role of Left Ventricular Remodeling and Reverse Remodeling in Heart Failure
- 13. Alterations in the Sympathetic and Parasympathetic Nervous Systems in Heart Failure
- 14. Alterations in the Peripheral Circulation in Heart Failure
- 15. Alterations in Kidney Function Associated with Heart Failure
- 16. Alterations in Skeletal Muscle in Heart Failure
- 17. Alterations in Cardiac Metabolism
Section 3 Etiological Basis for Heart Failure
- 18. Epidemiology of Heart Failure
- 19. Heart Failure as a Consequence of Ischemic Heart Disease
- 20. Heart Failure as a Consequence of Dilated Cardiomyopathy
- 21. The Restrictive and Infiltrative Cardiomyopathies and Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
- 22. Cardiac Amyloidosis
- 23. Heart Failure as a Consequence of Hypertrophic Cardiomyopathy
- 24. Heart Failure as a Consequence of Genetic Cardiomyopathy
- 25. Heart Failure as a Consequence of Hypertension
- 26. Heart Failure as a Consequence of Valvular Heart Disease
- 27. Heart Failure as a Consequence of Congenital Heart Disease
- 28. Heart Failure as a Consequence of Viral and Nonviral Myocarditis
- 29. Heart Failure in the Developing World
- 30. Heart Failure and Human Immunodeficiency Virus
Section 4 Clinical Assessment of Heart Failure
- 31. Clinical Evaluation of Heart Failure
- 32. Cardiac Imaging in Heart Failure
- 33. Biomarkers and Precision Medicine in Heart Failure
- 34. Hemodynamics in Heart Failure
Section 5 Therapy for Heart Failure
- 35. Disease Prevention in Heart Failure
- 36. Management of Acute Decompensated Heart Failure
- Guidelines
- 37. Contemporary Medical Therapy for Heart Failure Patients with Reduced Ejection Fraction Guidelines: Management of Heart Failure with a Reduced Ejection Fraction
- 38. Management of Arrhythmias and Device Therapy in Heart Failure
Guidelines - 39. Treatment of Heart Failure with Preserved Ejection Fraction
Guidelines - 40. Management of Heart Failure in Special Populations: Older Patients, Women, and Racial/Ethnic Minority Groups
- 41. Gene and Stem-Cell Based Therapies in Heart Failure
- 42. Neuromodulation in Heart Failure
- 43. Pulmonary Hypertension
- 44. Cardiac Transplantation
- 45. Circulatory Assist Devices in Heart Failure
- 46. Cardio-Oncology and Heart Failure
- 47. Disease Management and Telemedicine in Heart Failure
- 48. Management of Comorbidities in Heart Failure
- 49. Quality and Outcomes in Heart Failure
- 50. Decision Making and Palliative Care in Advanced Heart Failure
