- There is no book about Hypertension with such a concept in the existing literature in the field
- All the major hypertension trials discussed in a book – pros, cons, effects on international guidelines, unmet needs
- The reader will be introduced in the first section on how to read and understand a scientific paper
- Discusses major hypertension trials covering their effects on international guidelines and current medical practice
- Contains guidance for physicians and scientists on how to use biostatistics and to evaluate their use in trials
Features guidance on how to read scientific literature specific to hypertension medicine to gain the maximal understanding
This book is a valuable tool to assist both cardiovascular physicians and scientists learning the intricacies of hypertension research and its milestone studies. All major hypertension trials have been reviewed in this book in chronological order with extensive discussion of the study population, study design, and outcomes and with a special focus on what knowledge they offered, their strengths and weaknesses, statistical errors, impact on international guidelines and unmet needs. Importantly, the book also offers physicians and young scientists with basic knowledge regarding medical biostatistics. It is of critical importance for a scientist involved in the field to understand deeply the process of analyzing medical data. Moreover, the accurate interpretation of the results is central for applying evidence-based medicine in everyday clinical practice.
Management of Hypertension: Current Practice and the Application of Landmark Trials is a critical tool to assist in the education of physicians and researchers in the field, providing a separate section on pioneer researchers in hypertension and urging readers to become bright exemplars for scientists wishing to pursue a career in academic medicine and hypertension research.
Table of ContentsSECTION ONE: INTRODUCTION TO MEDICAL RESEARCH
- 1. The importance of applying evidence-based medicine in clinical practice
- 2. How to read and understand a scientific paper
- 3. Medical Biostatistics; The basics
SECTION TWO: MAJOR TRIALS IN HYPERTENSION RESEARCH
- 4. Is blood pressure related to increased cardiovascular risk?
- 5. The VA Cooperative Studies - The First RCTs of Hypertension anywhere in the world
- 6. What is the role of dietary modifications in controlling blood pressure?
- 7. Hypertension management in the elderly
- 8. Hypertension management in African Americans
- 9. Hypertension management in diabetics
- 10. Outcomes of different antihypertensive regimens
- 11. Comparison of combination therapies in the treatment of hypertension
- 12. What is the goal of treatment?
- 13. Can we prevent hypertension?
SECTION THREE: BLOOD PRESSURE ASSESSMENT METHODS USED IN LANDMARK TRIALS
- 14. Methods of blood pressure assessment used in milestone hypertension trials
SECTION FOUR: PIONEERS IN HYPERTENSION RESEARCH
- 15. Marvin Moser
- 16. Irvine Page
- 17. Edward Freis
- 18. Stevo Julius
SECTION FIVE: CLOSING REMARKS
- 19. The Future in Hypertension Research
