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Features:- Comprehensively covers the histopathological characterization, molecular mechanisms, and most recent therapeutic interventions in neuroblastoma
- Includes recent developments and therapeutic interventions for neuroblastoma, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy
- Presents a broad scope that provides basic researchers, practitioners and students with the most current overview of recent advances
Table of Contents:- 1. Neuroblastoma pathology and classification
- 2. Role of genetic and epigenetic alterations in pathogenesis of neuroblastoma
- 3. Neuroblastoma molecular biology and promising therapeutic targets
- 4. The GD2-targeted immunotherapy of neuroblastoma
- 5. Targeting angiogenesis in neuroblastoma
- 6. Autophagy and novel therapeutic strategies in neuroblastoma
- 7. Energy metabolism and new therapeutic opportunities in neuroblastoma
- 8. Multimodality imaging for diagnosis of neuroblastoma
- 9. Immunotherapy for neuroblastoma
- 10. Advances in surgical treatment of neuroblastoma
- 11. Role of stemness factors in neuroblastoma: Neuroblastoma stem cells, tumor microenvironment, and chemoresistance
- 12. Current pharmacotherapy for neuroblastoma
- 13. Current challenges in the management of neuroblastoma
- 14. Novel therapeutic targets in neuroblastoma
- 15. Current and future strategies for treatment of relapsed neuroblastoma
- 16. Current evidence in favor of a tumor suppressor role of Krüppel-like factor 4 in malignant neuroblastoma
- 17. Modulation of expression of microRNA as a therapeutic strategy in malignant neuroblastoma
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