- Presents the state of the art in multimodal, multiparametric preclinical imaging
- Combines scientific facts with easily readable text
- Explains the similarities and differences between preclinical and clinical applications of image fusion
- Includes numerous informative illustrations
- Serves as an ideal introduction for those who will wish to explore specific topics further
This book provides an accessible and comprehensive overview of the state of the art in multimodal, multiparametric preclinical imaging, covering all the modalities used in preclinical research.
The role of different combinations of PET, CT, MR, optical, and optoacoustic imaging methods is examined and explained for a range of applications, from research in oncology, neurology, and cardiology to drug development. Examples of animal studies are highlighted in which multimodal imaging has been pivotal in delivering otherwise unobtainable information. Hardware and software image registration methods and animal-specific factors are also discussed. The readily understandable text is enhanced by numerous informative illustrations that help the reader to appreciate the similarities to, but also the differences from, clinical applications.
Image Fusion in Preclinical Applications will be of interest to all who wish to learn more about the use of multimodal/multiparametric imaging as a tool for in vivo investigations in preclinical medical and pharmaceutical research.
Table of Contents- High-Level Story: Data Analysis in Multimodal Preclinical Imaging—Methods and Tools
- Instrumentation Challenges in (S)PE(C)T Systems
- Influence of Animal Handling and Housing on Multimodality Imaging
- Multimodal Optoacoustic Imaging
- Small Animal Imaging in Oncology Drug Development
- Investigation of Transporter-Mediated Drug-Drug Interactions Using PET/MRI
- Multimodality Preclinical Imaging in Inflammatory Diseases
- Preclinical Multimodality Imaging and Image Fusion in Cardiovascular Disease
- Dual-Energy SPECT Imaging with Contrast-Enhanced CT: A Case Study
- Multimodality Imaging in Small Animal Radiotherapy
