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Cardiovascular Thrombus - From Pathology and Clinical Presentations to Imaging, Pharmacotherapy and Interventions
Provides a comprehensive understanding of the pathophysiology, clinical presentations and diagnosis of cardiovascular thrombosisIncludes the most up-to-date information on the practical management of patients with thrombus related conditionsWritten by the leading experts in the fieldDelivers an explanation of the current and upcoming pharmacotherapy and technology available for thrombus research and treatmentTable of ContentsSection 1. Pathology1. Hemostasis and thrombosis2. Vascular wall pathology- effect on thrombosis3. Mechanisms of thrombosis and their relationship to atherosclerosis: Endothelial cell function and injury [trauma, infection]4. Platelet aggregation in the pathogenesis of vascular ischemia conditions5. Physical properties and morphologic features of thrombus6. Pathology of arterial thrombosis7. Thrombus types8. The calcified thrombus: histopathology9. Pathology of venous thrombosis10. Hypercoagulopathy: acquired syndromes and thrombosis11. Hypercoagulopathy: hereditary syndromes and thrombosis12. Intra cardiac thrombosis: ventricles, atria, appendage and valves13. Prosthetic surgical valves and TAVR thrombosis14. Closure devices and thrombosisSection 2. Clinical presentations15. Thrombotic ischemic syndromes of the coronary circulation16. Thrombotic ischemic syndromes of the brain17. Thrombotic syndromes of the peripheral arterial circulation18. Thrombosis of the splanchnic and mesenteric19. Unique thrombus-containing lesions20. Thrombosis of the venous system: DVT; portal vein; renal vein; Superior vena cava; Jugular; Budd-Chiari; cavernous sinus; cerebral21. The angry thrombus phenomenon and the simultaneous thrombus in different vascular beds22. Pulmonary embolism-acute23. Pulmonary embolism: chronic24. Platelets, thrombus and thrombosis in pregnancy25. Atrial fibrillation and thromboembolismSection 3. Diagnosis26. Cardiovascular Thrombus classifications27. Laboratory studies of thrombus and thrombosis28. Imaging modalitiesSection 4. Treatment Guidelines29. The role of treatment guidelines-comparing the US and European approach to cardiovascular thrombusSection 5. Pharmacotherapy30. From Coumadin to the new anticoagulation agents31. Antiplatelet agents: asa; heparins; LMH32. Direct thrombin inhibitors33. The 2b/3a receptor antagonists34. Thienopyridines35. Thrombolytic agentsSection 6. Interventions36. Percutaneous approach37. Protection filters38. Mechanical thrombectomy: Angiojet and X-Sizer39. Stents: dedicated thrombus containing stent platforms40. Extraction and vaporization devices: thrombocat and laser41. LAA closure42. Surgical approachSection 7. Future trends43. Pharmacotherapy and technology
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