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- A unique, up-to-date discussion of the history, indications and techniques for intracytoplasmic sperm injection (ICSI)
- Discusses sperm development, assessment and selection, microsurgical techniques for injection, and clinical approaches to fertility failure following ICSI
- A comprehensive resource for reproductive endocrinologists, andrologists, and infertility practitioners and researchers
This unique, comprehensive text on the male factor infertility experience centers on the current background, applications and techniques for intracytoplasmic sperm injection (ICSI), one of the more commonly utilized procedures in modern assisted reproduction for male infertility, offering insights into the rationale and indications for ICSI and providing an up-to-date discussion on male factor diagnostic tests and microsurgical techniques for ICSI itself. Topics covered include the role of reproductive genetics, the effects of paternal age, the assessment, development and selection of functional human spermatozoa (e.g., Comet assay), both naturally and in the laboratory, and the procedures by which these sperm are injected directly into an oocyte. Comparisons are made between efficacy rates of ICSI versus conventional IVF strategies, and clinical approaches to fertilization failures following ICSI are presented, and intracytoplasmic morphologically selected sperm injection (IMSI) is discussed in detail in a chapter of its own. Bringing together the latest evidence and written by international leaders in the field, Intracytoplasmic Sperm Injection: Indications, Techniques and Applications is a unique and accessible resource for reproductive endocrinologists, andrologists, geneticists and infertility practitioners and researchers alike. Table of Contents- Male-Factor Infertility: Factoring in the Male Experience
Diederik F. Janssen - Intracytoplasmic Sperm Injection: History, Indications, Technique, and Safety
Nigel Pereira, Gianpiero D. Palermo - The Role of Reproductive Genetics in Modern Andrology
Douglas T. Carrell, Timothy G. Jenkins, Benjamin R. Emery, James M. Hotaling, Kenneth I. Aston - Effect of Paternal Age on Reproductive Outcomes: Data from Intracytoplasmic Sperm Injection and Oocyte Donation
Lena Sagi-Dain, Martha Dirnfeld - New Paradigms in De Novo Creation of Functional Human Spermatozoa: A Review of Biological Progress Towards Clinical Application
Nina Neuhaus, Tim Pock, Stefan Schlatt, Verena Nordhoff - Assessment of Sperm DNA Integrity and Implications for the Outcome of ICSI Treatments
Preben Christensen, Anders Birck - Sperm Evaluation Using the Comet Assay
Océane Albert, Bernard Robaire - Automated Morphology Detection from Human Sperm Images
Seyed Abolghasem Mirroshandel, Fatemeh Ghasemian - Clinical Approaches to Male Factor Infertility
Omer A. Raheem, Tung-Chin Hsieh - Intracytoplasmic Morphologically Selected Sperm Injection (IMSI): An Overview
Daniel Luna Origgi, Javier García-Ferreyra - Implications of Sperm Source on ICSI Outcome: Assessment of TESE and Other Surgical Sperm Retrieval Methods
Nikita Abhyankar, Samuel Ohlander, Martin Kathrins - Intracytoplasmic Sperm Injection (ICSI): Applications and Insights
Toru Suzuki, Anthony C. F. Perry - The Human Y-chromosome: Evolutionary Directions and Implications for the Future of “Maleness”
Darren K. Griffin, Peter J. I. Ellis
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