- A case based learning of neuromuscular disorders
- Description of key differential clinical points
- Analysis of investigation in clinical context
- Guidance for genetic tests
- Comprehensive management guide
- Written by experts in the field
This book provides a concise overview of the diagnosis and therapy of a wide variety of neuromuscular disorders, in tabulated form and with illustrative cases.
Treating neuromuscular disorders calls for a sound, step-by-step clinical approach based on differential diagnosis and laboratory investigations. Yet to date, there has been no single, compact book that offers all the relevant information related to the management of these disorders.
This book fills that gap, presenting the state of the art in the field and addressing practical problems together with their solutions. Each chapter covers disorder characteristics, clinical differentiating points, relevant investigations and their interpretation, available genetic testing, best management approaches and counselling. Illustrative cases provide valuable insights, while extensive tables and illustrations mean that information can be rapidly found.
Table of ContentsPart I: Asymmetric motor weakness.
- - Motor Neuron Diseases [ALS].-
- Hirayama disease and other focal amyotrophies.-
- Multifocal motor neuropathy.-
- Acute motor axonal neuropathy.-
- Facioscapulohumeral muscular dystrophy.-
- Progressive muscular atrophy.-
- Post-polio syndrome.-
Part II: Symmetric proximal weakness.-
- Duchenne and Becker muscular dystrophies.-
- Spinal Muscular atrophy [SMA].-
- Idiopathic Inflammatory myopathies.-
- Limb Girdle muscular Dystrophies [LGMDs].-
- Congenital Myasthenic syndromes [CMS].-
- Congenital muscular dystrophies.-
- Congenital myopathies.-
- Emery Dreifuss Muscular dystrophy.-
- Oculopharyngeal muscular dystrophy.-
Part III: Symmetric distal weakness.-
- Myotonic dystrophies [DM].-
- Distal myopathies.-
- Distal hereditary motor neuropathies.-
- Brown Vieletto Van Laere Syndrome.-
Part IV: Fluctuating weakness.-
- Myasthenia Gravis [MG].-
- Lambert Eaton Myasthenic Syndrome.-
- Periodic paralysis.-
Part V: Exercise intolerance, muscle stiffness, cramps and contractures.-
- Metabolic myopathies.-
- Peripheral nerve hyperexcitability syndromes.-
- Non dystrophic myotonias.-
Part VI: Asymmetric sensory motor weakness.-
- Individual neuropathies.-
- Vasculitic neuropathy.-
- Multifocal acquired demyelinating sensory and motor neuropathy.-
- Brachial plexopathies.-
- Lumbosacral plexopathies.-
- Compressive Radiculopathies.-
- Leprosy.-
- Hereditary neuropathy with pressure palsy.-
Part VII: Symmetric sensory motor weakness.-
- Guillain-Barré syndrome.-
- Charcot-Marie-Tooth disease[CMT].-
- Chronic Inflammatory Demyelinating Polyradiculoneuropathy.-
- X-linked Charcot Marie Tooth disease.-
- Other Hereditary neuropathies –
- 1.- Other hereditary neuropathies –
- 2.- Neuropathies secondary to systemic diseases.-
- Porphyrias.-
Part VIII: Predominant sensory syndromes.-
- Sensory ganglionopathies.-
- Distal Acquired Demyelinating Symmetric neuropathy.-
- Paraproteinemic neuropathies.-
- Miller Fisher Syndrome.
