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OCT in Central Nervous System Diseases


GRZYBOWSKI / BARBONI --- Neuerscheinung!!

OCT in Central Nervous System Diseases
The Eye as a Window to the Brain

561 Seiten, 2. Auflage, 2020
159 Abbildungen

  • Update on the role of OCT in evaluating disease progression in neurodegenerative disorders
  • Broadens understanding of OCT imaging and interpretation
  • Presents translational aspects from animal models to the clinical approach
The second edition of OCT and Imaging in Central Nervous System Diseases offers updated state-of-the-art advances using optical coherence tomography (OCT) regrading neuronal loss within the retina. Detailed information on the OCT imaging and interpretation is provided for the evaluation of disease progression in numerous neurodegenerative disorders and as a biological marker of neuroaxonal injury.

Covering disorders like multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, intracranial hypertension, Friedreich’s ataxia, schizophrenia, hereditary optic neuropathies, glaucoma, and amblyopia, readers will given insights into effects on the retina and the and optic nerve. Individual chapters are also devoted to OCT technique, new OCT technology in neuro-ophthalmology, OCT and pharmacological treatment, and the use of OCT in animal models.

Similar to the first edition, this book is an excellent and richly illustrated reference for diagnosis of many retinal diseases and monitoring of surgical and medical treatment. OCT allows to study vision from of the retina to the optic tracts. Retinal axons in the retinal nerve fiber layer (RNFL) are non-myelinated until they penetrate the lamina cribrosa. Hence, the RNFL is an ideal structure for visualization of any process of neurodegeneration, neuroprotection, or regeneration. By documenting the ability of OCT to provide key information on CNS diseases, this book illustrates convincingly that the eye is indeed the “window to the brain”

Table of Contents
  • Introduction: Retina Imaging—Past and Present
  • OCT Technique: Past, Present and Future
  • The APOSTEL Recommendations
  • OCT Angiography: Guidelines for Analysis and Interpretation
  • Seeing the Brain Through the Eye: What Is Next for Neuroimaging and Neurology Applications
  • Advances in Retinal Imaging: Retinal Amyloid Imaging
  • Advances in Retinal Imaging: Real-Time Imaging of Single Neuronal Cell Apoptosis (DARC)
  • Retinal Oximetry in Central Nervous System Diseases
  • Optical Coherence Tomography and Optic Nerve Edema
  • OCT and Compressive Optic Neuropathy
  • OCT and Multiple Sclerosis
  • OCT in Parkinson’s Disease and Related Disorders
  • Optical Coherence Tomography in Alzheimer’s Disease
  • Friedreich’s Ataxia and More: Optical Coherence Tomography Findings in Rare Neurological Syndromes
  • Other Neurological Disorders: Migraine, Neurosarcoidosis, Schizophrenia, Obstructive Sleep Apnea-Hypopnea Syndrome and Bipolar Disorder
  • Hereditary Optic Neuropathies
  • Trans Neuronal Retrograde Degeneration to OCT in Central Nervous System Diseases
  • OCT in Toxic and Nutritional Optic Neuropathies
  • Animal Models in Neuro Ophthalmology
  • OCT in Glaucoma
  • OCT in Amblyopia
  • Pediatric Neuro-Ophthalmology and OCT
  • Machine Learning Approaches in OCT: Application to Neurodegenerative Disorders
  • Optical Coherence Tomography Angiography in Neurology and Neuro-Ophthalmology
  • Conclusion: The Exciting Future of OCT and New Imaging of Retina and Optic Nerve


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