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Short Course Breast Radiotherapy. A Comprehensive Review of Hypofractionation, Partial Breast, and Intra-Operative Irradiation


ARTHUR / VICINI / WAZER/ KHAN  

Short Course Breast Radiotherapy. A Comprehensive Review of Hypofractionation, Partial Breast, and Intra-Operative Irradiation

501 Seiten, Auflage, 2016
143 Abbildungen

  • Focuses on the use of accelerated forms of adjuvant radiotherapy for treatment of early-stage breast cancer
  • Provides comprehensive coverage of techniques and clinical implementation, spanning partial and whole breast treatment approaches
  • Written and edited by leaders in radiotherapy treatment techniques
This comprehensive handbook on the implementation of short course radiotherapy for the treatment of breast cancer is intended as an up-to-date resource for the clinician.

The book opens with a series of chapters on underlying principles and diverse relevant topics, including pathologic anatomy of early-stage breast cancer, radiobiology of accelerated breast irradiation, quality assurance and radiation safety, surgical considerations in partial breast irradiation, and impact of oncoplastic surgery on adjuvant radiotherapy. Individual sections are then devoted to hypofractionated whole breast radiotherapy, accelerated partial breast irradiation, and intraoperative radiotherapy. Each section includes details of patient selection, physics, techniques, data, and toxicity.

The reader is provided with clear guidance on the appropriate use of accelerated forms of adjuvant radiotherapy for treatment of early-stage breast cancer and on various emerging treatment approaches.

Table of Contents

Section I:
  • 1. Accelerated Breast Irradiation: History, Rationale, and Controversies
  • 2. Pathologic Anatomy of Early-Stage Breast Cancer: Defining the Target
  • 3. The Radiobiology of Accelerated Breast Irradiation
  • 4. Quality Assurance and Radiation Safety/Medical Events
  • 5. Surgical Considerations in Partial Breast Irradiation
  • 6.Impact of Oncoplastic Surgery on adjuvant XRT
  • 7. Comparison of true cost between modalities in a changing health care system
SECTION II: Hypofractionated WBI
  • 8. Patient Selection
  • 9. Physics of HWBI
  • 10. Treatment History- techniques/data/toxicity
SECTION III: APBI
  • 11. Patient Selection
  • 12. Physics of Accelerated Partial Breast Irradiation
  • 13. Interstitial brachytherapy – techniques/data/toxicity
  • 14. Intracavitary brachytherapy – techniques/data/toxicity
  • 15. 3D-Conformal external beam radiotherapy - techniques/data/toxicity
SECTION IV: IORT
  • 16. Patient Selection
  • 17. Physics of IORT
  • 18. 50 kV Photons: Targeted Intraoperative Radiotherapy (TARGIT) - techniques/data/toxicity
  • 19. Intraoperative Technique with Electrons- techniques/data/toxicity
SECTION V: Emerging treatment approaches
  • 20. Extreme hypofractionation
    (brachytherapy, Gammapod, UK FAST WBI)21. APBI for breast augmentations
  • 22. Accuboost
  • 23. APBI for in-breast recurrence following WBI
  • 24. Preoperative partial breast
  • 25. Locoregional Hypofractionation
SECTION VI: Hypofractionation for metastatic disease
  • 26. Stereotactic treatment for Oligometastatic disease
  • 27. Hypofractionaton for palliation

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