- Enables surgeons to make informed daily decisions on anticoagulation and hemostasis
- Discusses anticoagulation issues raised by the emergence of new drugs
- Summarizes current guidelines and best practices
This book is an up-to-date reference on all aspects of anticoagulation and hemostasis in neurosurgery. After an opening section on basic principles and drug classes in current use, detailed consideration is given to coagulation issues relevant to all patients, not just neurosurgical ones. The coverage includes, for example, deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of important issues specific to neurosurgical practice are then addressed, and a summary of current guidelines and best practices is provided.
By bringing together the latest knowledge from across the discipline, this book will serve as a sound basis for informed decision making in surgical practice. It will be of daily value for neurosurgeons and trainees worldwide and will also be of interest to emergency room physicians, surgeons in general, critical care physicians, neurologists, and hospital medicine specialists.
Table of ContentsGeneral Principles:
- Physiology of Coagulation
- History and Pharmacology of Anticoagulation
- Measurement of Coagulation
- Current anticoagulant drugs and mechanisms of action
- Overview of Platelet Function
- Treatment, Measurement, and Modification of Platelet Function
- Congenital Coagulation Disorders
- Acquired Coagulation Disorders
- Heparin Induced Thrombocytopenia - HIT
Coagulation Issues Across all Patient Spectrums:
- Prophylactic Screening for Thrombotic Disease (DVT)
- Prophylactic Treatment of Thrombotic Disease (DVT)
- Workup and Treatment of Pulmonary embolus
- Treatment of DIC
- Considerations for Coagulation in the Multi-Trauma Patient
- Classes of drugs and blood products for acute reversal of anticoagulant effect
- Risks associated with administration of allogeneic blood products
Coagulation Issues Specific to Neurosurgery:
- Treatment of Dural Sinus Thrombosis
- Management of Rhythm Disturbances and Valvular Disease and the need for Anticoagulation in Neurosurgical Patients
- Coagulation studies in preoperative neurosurgical patients
- Safe strategies for gradual suspension and re-institution of anticoagulation to permit elective surgery
- Spontaneous ICH due to coagulation disorders.- Rescue strategies to facilitate emergency neurosurgery in anticoagulated patients
- DVT prophylaxis in neurosurgical patients
- Can Patients with known intracranial or intraspinal vascular lesions be anticoagulated?
Guidelines and Recommendations Summary.
