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- Authors are leaders in the development of fluorescent methods worldwide
- Richly illustrated with photomicrographs, figures and illustrations
- Provides the foundation to understand the current scope and limits of the use of fluorescence in surgery
This volume presents the experiences of leading researchers and surgeons with different fluorescence methods. Chapters range from basic science of fluorescence to current clinical applications and new horizons. The first few chapters cover the historical evolution and physical principles of fluorescence and provide the foundation for the reader to understand the current scope and limits of its use in surgery. The second section focuses on the clinical applications of intraoperative fluorescence imaging, including subsections on fluorescence cholangiography, applications to hepatectomy, lymph node navigation, applications to GI tract and pelvic surgery and identification of cancer tissues. The third section focuses on new frontiers including fluorescence probes, imaging systems and applications to photodynamic therapy. Authored by leaders in the development of fluorescent methods worldwide, Fluorescence Imaging for Surgeons: Concepts and Applications will have an impact on numerous medical specialists including general surgeons, colorectal and minimally-invasive surgeons and surgical oncologists. Researchers will find the book to be an invaluable resource on the latest advances in the utilization of nanoparticles and fluorescent probes. Table of ContentsSection I: Background - Chapter 1 Basic Concepts of Fluorescence and Fluorescent Probes
Guillermo O. Menéndez, Federico Coluccio Leskow, and Carla C. Spagnuolo - Chapter 2 Past, Present and Future of Fluorescence
Daniel Debonis, Pablo Quadri, Manuel Montesinos, Jorge Falco, David Nguyen, Diego Sinagra, Fernando Dip, and Raul J. Rosenthal - Chapter 3 Translation of Therapeutic Antibodies for Intraoperative Fluorescence Imaging
Eben L. Rosenthal and Jason M. Warram - Chapter 4 Review of Indocyanine Green Imaging in Surgery
Jarmo T. Alander, Outi M. Villet, Tommi Pätilä, Ilkka S. Kaartinen, Martin Lehecka, Toshiya Nakaguchi, Taku Suzuki, and Valery Tuchin
Section II: Imaging Systems - Chapter 5 D-Light P System (Karl Storz) (with video)
Rutger M. Schols, Nicole D. Bouvy, Ronald M. van Dam, Laurents P.S. Stassen - Chapter 6 Robotic surgery using Firefly System
Giuseppe Spinoglio, Alessandra Marano, Giampaolo Formisano - Chapter 7 Fluorescence imaging systems (PDE, HyperEye Medical System, and prototypes in Japan)
Takeaki Ishizawa and Norihiro Kokudo - Chapter 8 The Pinpoint System
Jana L. Lewis and Danny A. Sherwinter - Chapter 9 Economic Impact of Fluorescent Cholangiography
Emanuele Lo Menzo, Fernando Dip, Samuel Szomstein, and Raul J. Rosenthal - Chapter 10 Real-time near-infrared fluorescent cholangiography during robotic single-site cholecystectomy
Nicolas C. Buchs - Chapter 11 Fluorescent guided liver surgery: Paul Brousse experiences and perspective
Mohamed Bekheit and Eric Vibert - Chapter 12 Fluorescence imaging in laparoscopic hepatectomy (with video)
Yoshikuni Kawaguchi, Takeo Nomi, David Fuks, Norihiro Kokudo, and Brice Gayet
Section III. Clinical Applications of Intraoperative Fluorescence Imaging - Chapter 13 Identification of hepatic segment (with video)
Masaki Ueno - Chapter 14 Intraoperative evaluation of regional portal uptake function (with video)
Yoshikuni Kawaguchi, Takeaki Ishizawa, and Norihiro Kokudo - Chapter 15 Identification of hepatocellular carcinoma (with video)
Yoshifumi Morita, Takanori Sakaguchi, Hirotoshi Kikuchi, Naoki Unno, and Hiroyuki Konno - Chapter 16 Identification of metastatic liver cancer (with video)
Henricus J.M. Handgraaf, Floris P.R. Verbeek, Cornelis J.H. van de Velde, Merlijn Hutteman, and Alexander L. Vahrmeijer - Chapter 17 Prediction for postoperative intrahepatic recurrence of hepatocellular carcinoma
Kunihito Gotoh, Shigeru Marubashi, Terumasa Yamada, Hirofumi Akita, Hidenori Takahashi, Masahiko Yano, Osamu Ishikawa, Masato Sakon - Chapter 18 Detection of bile leakage after hepatic resection by intraoperative indocyanine green fluorescent imaging
Masaki Kaibori, Kosuke Matsui, Morihiko Ishizaki, Masanori Kwon - Chapter 19 Near-infrared laser photodynamic therapy for human hepatocellular carcinoma cell line tumor with indocyanine green fluorescence
Junichi Kaneko, Yoshinori Inagaki, Takeaki Ishizawa, Norihiro Kokudo - Chapter 20 Photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid (with video)
Tsutomu Namikawa, Keiji Inoue, Taro Shuin, and Kazuhiro Hanazaki - Chapter 21 Applications of ICG Fluorescence Imaging for Surgery in Colorectal cancer
Shingo Shimada, Seiji Ohtsubo, and Mitsuo Kusano - Chapter 22 Fluorophore-conjugated chimeric anti-CEA antibodies for fluorescence-guided surgery of gastrointestinal (GI) tumors
Michael Bouvet and Robert M. Hoffman - Chapter 23 Development of a non-blurring, dual-imaging (X-ray/fluorescence) tissue marker for localization of gastrointestinal tumors
Hideki Hayashi, Taro Toyota, Shoichi Goto, Aki Oishi, Tao Gao, Lau Bik Ee, Hisahiro Matsubara - Chapter 24 Sentinel Node Navigation Surgery by Infrared Imaging in Gastric Cancer
Yoshikazu Uenosono, MD, Takaaki Arigami, Shigehiro Yanagita, Daisuke Matsushita, Sumiya Ishigami, and Shoji Natsugoe - Chapter 25 A dual infrared ray imaging system for sentinel node mapping against early gastric cancer: absorption and florescence methods by infrared ray electronic endoscopy combined with indocyanine green
Naoto Takahashi, Hiroshi Nimura, Muneharu Fujisaki, Norio Mitsumori, and Katsuhiko Yanaga - Chapter 26 Indocyanine green fluorescence-navigated sentinel node biopsy showed higher sensitivity than the conventional radioisotope or blue dye methods: it may help to reduce false-negative sentinel lymph node biopsies in skin cancer
Yasuhiro Fujisawa - Chapter 27 The indocyanine green method is equivalent to the (99m)Tc-labeled radiotracer method for identifying the sentinel node in breast cancer: A concordance and validation study
Bettina Ballardini, Germana Lissidini, and Paolo Veronesi - Chapter 28 Photodynamic detection of lymph node metastases in gastrointestinal cancer by using 5-aminolevulinic acid
Takeo Minamikawa, Yoshinori Harada, and Tetsuro Takamatsu - Chapter 29 Application of photodynamic treatment (with video)
Tomás G. Núñez and Tamara Portas - Chapter 30 Photodynamic diagnosis mediated by 5-aminolevulinic acid for urinary bladder cancer (with video)
Keiji Inoue, Hideo Fukuhara, and Taro Shuin - Chapter 31 Real-time assessment of intestinal perfusion by fluorescence-based enhanced reality
Michele Diana, Vincent Agnus and Jacques Marescaux - Chapter 32 Fluorescent angiography for flap planning and monitoring in reconstructive surgery
Georges Bettega, Clotilde Ochala, Marine Hitier, Cynthia Hamou¸ Stéphanie Guillermet, Pascal Gayet, and Jean-Luc Coll - Chapter 33 Fluorescein-Detection of Myocardial Ischemia in an Experimental Model of Acute Coronary Occlusion
Fernando Dip, Alejandro Damonte, Gaston Quiche, Marcelo Damonte, Fernando M. Safdie, Nicolas Brozzi, and Raul J. Rosenthal - Chapter 34 Spatial and Temporal Monitoring of Perfusion with Indocyanine Green Videoangiography in Rat Heart
Outi M. Villet, Jarmo T. Alander, and Ari L. Harjula - Chapter 35 Ureter identification using methylene blue and fluorescein
Fernando Dip, Alejandro Daniel Moreira Grecco, David Nguyen, Luis Sarotto, Sandy Perrins, and Raul J. Rosenthal - Chapter 36 Chymotrypsin probe for real-time visualization of pancreatic leak
Suguru Yamashita, Takeaki Ishizawa, Masayo Sakabe, Mako Kamiya, Yasuteru Urano, and Norihiro Kokudo
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