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- Different strategies used to increase resectability in patients with colorectal liver metastases including tactics, technics, tips and tricks
- The book shows that no patient is unresectable before getting overview by experienced surgeons in extreme hepatic surgery
- A multidisciplinary approach for the disease describing diagnoses and staging, preoperative and anesthetic’s management and surgical strategies
- Participation of internationally known reference specialists on their fields
This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients. Table of Contents- Liver Surgical Anatomy
Bismuth, Henri (et al.) - Resectability Assessment with Diagnostic Imaging
Sterkenburg, Anthe (et al.) - Preoperative Evaluation of Liver Function
Cieslak, Kasia P. (et al.) - Imaging-Based Preoperative Planning
Mittler, Jens (et al.) - Choosing the Best Strategy
Ardiles, Victoria (et al.) - Conversion and Neoadjuvant Therapies
Grondona, Jorge Pablo - Portal Vein Embolization
Brudvik, Kristoffer Watten (et al.) - Intra-Arterial Chemotherapy
Chandwani, Rohit (et al.) - Radioembolization
Garcia-Mónaco, Ricardo - Anesthetic Management
Bonofiglio, Francisco Carlos - Intraoperative Evaluation of Resectability
Torzilli, Guido (et al.) - Vascular Control in Major Hepatic Resections
Bork, Ulrich (et al.) - Two-Stage Liver Surgery
Imai, Katsunori (et al.) - Two-Stage Liver Surgery with Portal Vein Occlusion
Linecker, Michael (et al.) - Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
Alvarez, Fernando A. (et al.) - Parenchymal-Sparing Liver Resections
Ferrero, Alessandro (et al.) - Combined Vascular Resections
Arita, Junichi (et al.) - Ex-Vivo Liver Surgery
Felix Broelsch, G. (et al.) - The Role of Laparoscopy in Advanced Liver Disease
Pekolj, Juan (et al.) - Liver Transplantation for Unresectable Disease
Line, Pål-Dag (et al.) - Lung Metastases
Call, Sergi (et al.) - Nodal Involvement
Narita, Masato (et al.) - Peritoneal Metastases
Goéré, Diane (et al.) - Adjacent Organs Invasion: Multivisceral Resections
Santibañes, Martin - Postoperative Complications and Their Management
Pekolj, Juan (et al.) - Improving Quality of Life in Patients with Unresectable Disease
Bertolino, Mariela (et al.)
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