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- Presents the key physical principles and clinical applications of functional BOLD MRI
- Explores clinical applications of BOLD functional MRI in motor, sensory, language, and cognitive systems
- Examines the use of BOLD functional MRI in epilepsy, psychiatric disorders, neurodegenerative disorders, and psychopharmacology
- Covers the technical and clinical challenges associated with functional BOLD MRI
This book presents the basic principles and new and emergent clinical applications of BOLD fMRI. It describes the physical principles of BOLD fMRI imaging and reviews scanning methodologies, data analysis, challenges and limitations of BOLD fMRI, neurovascular uncoupling, and functional connectivity. The book also explores current and future clinical applications of BOLD fMRI in the fields of language, memory, fMRI WADA, visual pathway, brain mapping of eloquent cortex, pediatrics, auditory pathways, epilepsy, psychiatric disorders, neurodegenerative disorders, pharmacological applications, and cognitive neuroscience. It concludes with a discussion of BOLD fMRI paradigms that can be used for clinical and cognitive experiments. Derived from Faro, Mohamed, Law, and Ulmer’s Functional Neuroradiology: Principles and Applications, this book is a valuable resource for neurologists, cognitive neuroscientists, and neuroradiologists. Table of ContentsPart I BOLD Functional MRI: Physical Principles - 1. Principles of BOLD Functional MRI - Seong-Gi Kim and Peter A. Bandettini
- 2. fMRI Scanning Methods - Alexander B. Pine and Feroze B. Mohamed
- 3. Experimental Design and Data Analysis for fMRI - Geoffrey K. Aguirre
- 4. Challenges in fMRI and Its Limitations - R. Todd Constable
- 5. Neurovascular Uncoupling in Functional MR Imaging - Jorn Fierstra and David John Mikulis
- 6. Functional Connectivity MR Imaging - Michelle Hampson, Xilin Shen, and R. Todd Constable
- 7. Clinical Challenges of Functional MRI - Nader Pouratian and Susan Y. Bookheimer
Part II Neuroanatomical Atlas - 8. Neuroanatomical Atlas of Key Presurgical and Cognitive Eloquent Cortex Regions - Feroze B. Mohamed, Michael Yannes, Muhammed Malik, and Scott H. Faro
Part III BOLD Functional MRI: Clinical Applications - 9. fMRI of Language Systems: Methods and Applications - Jeffrey R. Binder
- 10. Functional MRI Studies of Memory in Aging, Mild Cognitive Impairment, and Alzheimer’s Disease - Shannon L. Risacher, Heather A. Wishart, and Andrew J. Saykin
- 11. fMRI Wada Test: Prospects for Presurgical Mapping of Language and Memory - Brenna C. McDonald, Jacob Kean, and Andrew J. Saykin
- 12. fMRI of Human Visual Pathways - Edgar A. DeYoe, John L. Ulmer, Wade Mueller, Lotfi Hacein-Bey, Viktor Szeder, Mary Jo Maciejewski, Karen Medler, Danielle Reitsma, and Jedediah Mathis
- 13. Brain Mapping for Neurosurgery and Cognitive Neuroscience - Joy Hirsch
- 14. Pediatric Applications of fMRI - Nolan R. Altman and Byron Bernal
- 15. fMRI of the Central Auditory System - Deborah A. Hall
- 16. fMRI of Epilepsy - Karsten Krakow
- 17. Applications of fMRI to Psychiatry - Melissa Lopez-Larson and Deborah A. Yurgelun-Todd
- 18. Applications of fMRI to Neurodegenerative Disease - Shamseldeen Y. Mahmoud, Stephen E. Jones, and Michael D. Phillips
- 19. Applications of MRI to Psychopharmacology - Dan J. Stein, Yihong Yang, and Betty Jo Salmeron
- 20. Functional MRI: Cognitive Neuroscience Applications - Mark D’Esposito, Andrew S. Kayser, and Anthony J.W. Chen
Part IV BOLD fMRI Paradigms - 21. BOLD fMRI Paradigms - Feroze B. Mohamed and Scott H. Faro
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