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A thorough overview of the contents of the book is planned in all key areas of developing knowledge and practice, both in the text in the printed book and that additional information which is provided in the accompanying ebook and online versions. A revision of the design of the printed book will enhance its appearance with a clearer range of headings and other text features. - Anatomy chapter: an expansion of the details on ocular and orbital anatomy; new images of the dural venous system and cerebral circulation; and new information on dural lymphatics.
- Embryology chapter: new material on melanocyte development in choroid.
- Genetics chapter: a full update of the clinical and northern blotting sections; in genomics an overview of the exome and whole genome, what it is and what it is used for; a discussion in proteomics of mass spectrometry; and in the gene therapy section references to CrispR technology; RNA sequencing and the re-evaluation of GWAS studies.
- Biochemistry and cell biology chapter: a full update of the introductory text on cells and tissues including the newly discovered organelles and their intracellular organisation; additional text on morphogenesis, and morph-omics; additional text demonstrating the barriers in the eye, flow of fluid within the eye and the biochemistry of corneal collagen crosslinking.
- Physiology of vision chapter: an increase in the coverage of anatomy of the cranial nerves will be combined with the relevant material on neurophysiology in this chapter. In addition there will be new material relating to clock genes and effects on visual function, non-ocular photoreception, and new studies on extensive parcellation in the brain will be included.
- Pharmacology chapter: revision of this chapter will include updates in the ocular pharmacology and drug delivery sections.
- Immunology chapter: a major revision of this section will transfer appropriate material to the eBook; in addition there will be updates on ocular immunology eg inflammation in AMD and glaucoma.
- Infection chapter: there will be new information on viruses such as Ebola, Zika, Chikungunya, CMV in immunocompetent individuals and Dengue.
- Pathology chapter: There will be updates of terminology / definition of vasculitis pathology; and new text on "liquid biopsy" emphasising optimal handling of sample delivery to the pathologist.
Key Features- The only all-embracing textbook of the basic sciences suitable for trainee ophthalmologists, optometrists and vision scientists.
- Utilising an attractive page design with over 300 colour drawings and 200 photographs this is an attractive and accessible text to learn from.
- The text presents in a readable form an account of all the basic sciences necessary for an understanding of the eye – anatomy, embryology, genetics, biochemistry, physiology, pharmacology, immunology, microbiology and infection and pathology.
Table of Contents- 1 Anatomy of the eye and orbit.
- 2 Embryology and early development of the eye and adnexia.
- 3 Genetics.
- 4 Biochemistry and cell biology.
- 5 Physiology of vision and the visual system.
- 6 General and ocular pharmacology.
- 7 Immunology.
- 8 Microbiology and infection.
- 9 Pathology.
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