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- Written by experts in the field
- This book provides in-depth information for clinicians to allow them to appreciate the wide range of clinical presentations with myasthenia gravis
- Unique to this edition are the chapters on animal models of myasthenia gravis, clinical trial development for myasthenia gravis, and emerging therapies for myasthenia gravis
The third edition of this important, gold-standard title outlines a range of significant advances in the study and understanding of myasthenia gravis. The overarching goal of this new edition is identical to the first and second -- to provide the clinician and the scientist with a common resource for understanding the profound achievements in the clinical, translational, and basic sciences of neuromuscular transmission disorders. In addition to several new authors and an extensive update of all chapters, this third edition includes summaries of pre-clinical research standards for autoimmune MG, along with a broad summary of MG clinical trial performance. The now greater understanding of the clinical presentation of MuSK-related MG and identification of potential new autoantigens, including LRP-4, is discussed. The development of treatment guidelines by groups in Japan, the United Kingdom, Germany, and an international consortium is also outlined. Myasthenia Gravis and Related Disorders, Third Edition, is an invaluable resource for meeting the many and varied needs of clinicians who treat patients with myasthenia gravis. Table of Contents- Neuromuscular Junction Physiology and Pathophysiology
Jaap J. Plomp - Acetylcholine Receptor Structure
Jie Luo, Jon M. Lindstrom - Immunopathogenesis of Myasthenia Gravis
Rozen Le Panse, Sonia Berrih-Aknin - Animal Models of Myasthenia Gravis for Preclinical Evaluation
Linda L. Kusner, Rozen Le Panse, Mario Losen, William D. Phillips - Epidemiology and Genetics of Myasthenia Gravis
Melissa Nel, Jeannine M. Heckmann - Clinical Presentations of Myasthenia Gravis
Jan B. M. Kuks - Ocular Myasthenia
Sui Hsien Wong, Michael Benatar - Thymoma-Associated Myasthenia Gravis
Alexander Marx, Philipp Ströbel, Cleo-Aron Weis - Electrodiagnosis of Neuromuscular Junction Disorders
Christopher David Geiger, Bashar Katirji - Autoantibody Testing in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases
Michelangelo Cao, Angela Vincent - Treatment of Myasthenia Gravis
Henry J. Kaminski - Neurocritical Care of Myasthenic Crisis
Jose Americo M. Fernandes, Jose I. Suarez - Thymectomy for Non-thymomatous Myasthenia Gravis
Joshua R. Sonett, Bianca Bromberger, Alfred Jaretzki III - Lambert-Eaton Syndrome
C. Michel Harper, Vanda A. Lennon - Acquired Neuromyotonia
Hakan Cetin, Angela Vincent - Congenital Myasthenic Syndromes
David Beeson - Toxic Neuromuscular Transmission Disorders
James F. Howard Jr. - Predictors of Psychological Health in Myasthenia Gravis
Robert H. Paul, Paola García-Egan - Myasthenia Gravis: Classification and Outcome Measurements
Nicholas J. Silvestri, Gil I. Wolfe - Emerging Therapeutics for Myasthenia Gravis
Anna Rostedt Punga, Henry J. Kaminski, Jeffrey T. Guptill - Clinical Trial Design for Myasthenia Gravis
Radwa Aly, Gary R. Cutter, Henry J. Kaminski
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